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Systematic reviews
26 records available.

Systematic, scoping, umbrella, and meta-analytic records with methods and limitations still requiring appraisal.

Educational boundary. Automatically detected metadata is not a medical conclusion, endorsement, or quality rating. Open the source, examine methods and population, and wait for appropriate review before applying a finding.

Ledger source: Database ledger. Last collected/checked: Nov 13, 2026, 5:16 AM UTC. This ledger timestamp is within the last 48 hours.

systematic-review
submitted

Ketamine for co-occurring chronic pain and depression: A scoping review highlighting the dual-outcome evidence gap and its treatment and research implications.

The journal of pain · Date not supplied

ketamineclinical-evidence

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Efficacy and safety of ketamine for post-traumatic stress disorder: A systematic review with narrative synthesis and consideration of military and veteran populations.

PCN reports : psychiatry and clinical neurosciences · Date not supplied

ketaminesafetyclinical-evidenceveterans

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

meta-analysis
submitted

Efficacy and safety of psilocybin-assisted therapy for alcohol use disorder: A systematic review and meta-analysis.

Journal of psychopharmacology (Oxford, England) · Date not supplied

psilocybinsafetyclinical-evidence

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

From Evidence to Practice: A Systematic Review of Implementation of Psychedelic-Assisted Psychotherapy.

Psychedelic medicine (New Rochelle, N.Y.) · Date not supplied

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Psilocybin-Assisted Therapy for Cancer-Related Psychological and Existential Distress in Adults with Cancer: An Integrative Systematic Review.

Journal of pain & palliative care pharmacotherapy · Date not supplied

psilocybin

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Exploring the durability of esketamine and ketamine's antidepressant effects in the maintenance phase of treatment: A systematic review.

Psychiatry research · Date not supplied

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Subacute and long-term changes in cognitive functioning after administration of classic psychedelics, MDMA and ketamine: A systematic review of clinical and preclinical evidence.

Neuroscience and biobehavioral reviews · Date not supplied

ketaminemdma

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

meta-analysis
submitted

Efficacy and Safety of Psychedelic Microdosing on Psychological Outcomes in Healthy Adults: A Systematic Review and Meta-analysis.

CNS drugs · Date not supplied

safetyclinical-evidence

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

A rapid systematic review of palliative uses of ketamine for depression and pain in people living with advanced cancer.

Annals of palliative medicine · Date not supplied

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

The effect of ketamine on mitochondrial bioenergetics, viability, and function: A systematic review.

Journal of psychopharmacology (Oxford, England) · Date not supplied

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Ketamine for co-occurring chronic pain and depression: A scoping review highlighting the dual-outcome evidence gap and its treatment and research implications.

Europe PMC · 11/9/2026

ketamineclinical-evidence

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Psilocybin-Assisted Therapy for Cancer-Related Psychological and Existential Distress in Adults with Cancer: An Integrative Systematic Review.

Europe PMC · 11/3/2026

psilocybin

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

From Evidence to Practice: A Systematic Review of Implementation of Psychedelic-Assisted Psychotherapy.

Europe PMC · 11/2/2026

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Exploring the durability of esketamine and ketamine's antidepressant effects in the maintenance phase of treatment: A systematic review.

Europe PMC · 10/29/2026

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

meta-analysis
submitted

Efficacy and Safety of Etomidate Versus Ketamine for Endotracheal Intubation in Critically Ill Patients: A Systematic Review and Meta-Analysis

Europe PMC · 10/19/2026

ketaminesafetyclinical-evidence

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Ketamine in psychiatry: a systematic review of clinical applications, safety considerations, and emerging challenges

Europe PMC · 10/19/2026

ketaminesafety

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Psilocybin for anhedonia in unipolar and bipolar depression: A systematic review of clinical and preclinical evidence.

Europe PMC · 10/19/2026

psilocybin

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

meta-analysis
submitted

Effects of Ketamine and Esketamine on Postoperative Delirium After General Anesthesia: A Meta-Analysis and Meta-Regression Analysis.

Europe PMC · 10/16/2026

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

meta-analysis
submitted

Safety, efficacy, and opioid-sparing effects of ketamine for analgesia in traumatic chest injury and rib fractures: a systematic review and meta-analysis

Europe PMC · 10/16/2026

ketaminesafetyclinical-evidence

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Ketamine use in the refractory and super refractory status epilepticus: a systematic review

Europe PMC · 10/6/2026

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Comparison of propofol fentanyl versus propofol ketamine for painless gastrointestinal endoscopy: a systematic review

Europe PMC · 10/6/2026

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

Comment on "Urological symptoms following ketamine treatment for psychiatric disorders: A systematic review".

Europe PMC · 9/29/2026

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

meta-analysis
submitted

MDMA-Assisted Therapy May Decrease PTSD Symptoms, Dissociation, Depression, and Functional Disability: A Systematic Review and Meta-Analysis.

Europe PMC · 9/9/2026

mdmaveterans

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

meta-analysis
submitted

Electroconvulsive Therapy vs. Ketamine: A Scoping Review and Meta-Analysis of Rapid-Acting Interventions for Acute Suicidality in Adults

Europe PMC · 9/4/2026

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

meta-analysis
submitted

A response to the letter to editor: Breaking the chains of depression: A systematic review and meta-analysis of psilocybin therapy.

Europe PMC · 9/2/2026

psilocybin

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

systematic-review
submitted

846. Inconsistent trial risk-of-bias judgements across psychedelic-assisted psychotherapy systematic reviews

Europe PMC · 9/1/2026

clinical-evidence

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

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