Imperial College London · 1/29/2025

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clinical-trial
submitted

Wellcome Leap Psilocybin for OUD

University of Pennsylvania · 1/22/2025

psilocybin

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clinical-trial
submitted

ketamine

Automated discovery metadata only. Human editorial and qualified review are required before interpreting findings or changing care.

Open source

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Clinical trials194 records available.

Adapted Massed Exposure Therapy Enhanced with MDMA for PTSD (aMETEMP): A randomized, double-masked protocol adapted for Veterans Affairs healthcare system.

Safety and efficacy of psilocybin-assisted therapy for alcohol use disorder: Open-label extension of a phase II randomized controlled trial.

Dexmedetomidine versus Subanaesthetic Ketamine for Opioid-sparing Anaesthesia During Lumbar Spine Surgery Under a Standardised Surgical Pleth Index-guided Analgesic Protocol: A Randomised Controlled Trial.

Effects of psilocybin with psychological support on anhedonia in treatment-resistant depression: A randomized controlled pilot trial.

Randomized controlled trial of acute ketamine versus midazolam for recurrence of suicidality in adolescents (TASK): Rationale, design, and baseline characteristics.

Stellate Ganglion Block Combined With Subanesthetic Ketamine Versus Dexmedetomidine for the Management of Paroxysmal Sympathetic Hyperactivity (PSH) After Traumatic Brain Injury: A Randomized Trial.

Working memory neural correlates after ketamine in treatment-resistant depression: a randomized placebo-controlled functional magnetic resonance imaging study.

Intermittent theta burst stimulation to extend early ketamine response in treatment-resistant depression: A preliminary enriched randomized, double-blind, sham-controlled trial.

MDMA-assisted therapy for social anxiety disorder: A randomized, open-label, wait-list controlled trial.

Intravenous Ketamine reduces psychological pain in suicidal inpatients: A secondary analysis of a six-week randomized placebo-controlled trial.

Ketamine Plus Midazolam versus Fentanyl Plus Midazolam for Sedation and Analgesia during Image-guided Procedures in Interventional Radiology: Randomized Clinical Trial.

Ketamine assisted psychotherapy to reduce chronic neuropathic pain: A mixed-methods randomized pilot trial.

Ketamine Analgesia for Refractory Mucositis Pain (KARM): A prospective, double-blind, randomised, phase 2 study of ketamine for oral and pharyngeal mucositis pain.

Serial Ketamine Infusions for Treatment-Resistant Bipolar Depression: A Randomized Clinical Trial.

Ketamine for Analgosedation in Mechanically Ventilated Adults: A Double-Blind Randomized Trial.

Comparison of subanaesthetic ketamine and lidocaine as adjuvants to propofol-based total intravenous anesthesia on propofol requirement during emergency decompressive craniectomy for traumatic brain injury: a prospective, double-blind, three-arm randomized controlled trial.

How Does Psilocybin Affect Daily Life Experience and Behavior? Protocol For a Multimethod Ambulatory Assessment Study Within a Clinical Trial of Psilocybin for Depression

Low-Dose Propofol, Ketamine, and Their Combination for the Prevention of Post-Extubation Cough and Laryngospasm in Patients Undergoing Gynecologic Laparotomy: A Randomized Controlled Trial

MDMA-assisted therapy for social anxiety disorder: A randomized, open-label, wait-list controlled trial.

Intermittent theta burst stimulation to extend early ketamine response in treatment-resistant depression: A preliminary enriched randomized, double-blind, sham-controlled trial.

Stellate Ganglion Block Combined With Subanesthetic Ketamine Versus Dexmedetomidine for the Management of Paroxysmal Sympathetic Hyperactivity (PSH) After Traumatic Brain Injury: A Randomized Trial.

Preoperative emotional stress and postoperative pain after lumbar fusion surgery: secondary analysis of a randomized trial of adjunctive S-ketamine in oxycodone patient-controlled analgesia

Working memory neural correlates after ketamine in treatment-resistant depression: a randomized placebo-controlled functional magnetic resonance imaging study.

Changes in self-related cognitive processes and depressive symptom severity following a single, moderate dose of psilocybin in depressed patients.

Effects of psilocybin with psychological support on anhedonia in treatment-resistant depression: A randomized controlled pilot trial.

Psilocybin, cognitive stability and drinking reduction in co-occurring alcohol use disorder and depression: a pilot secondary analysis of a randomized, placebo-controlled trial

Effects of Bolus Versus Infusion Ketamine During Laparoscopic Cholecystectomy

Adapted Massed Exposure Therapy Enhanced with MDMA for PTSD (aMETEMP): A randomized, double-masked protocol adapted for Veterans Affairs healthcare system.

Single Intranasal Administration of the Psychedelic Mebufotenin for Treatment-Resistant Depression: A Randomized Clinical Trial.

Effects of Different Doses of Ayahuasca on Personality in Healthy Volunteers

Dexametedomidine Ketamine Infusion Versus Dexametedomidine Propofol Infusion in Non-compliant Agitated Patients on Continuous Positive Airway Pressure (CPAP) Mask Ventilation in the Intensive Care Unit

Psilocybin and Inflammatory and Mitochondrial Stress Markers in Parkinson Disease: A Nonrandomized Clinical Trial.

Evaluation of the Effects of Different Doses of Ayahuasca on Intelligence and Verbal Memory in Healthy Volunteers: A Preliminary, Exploratory, Double-Blind, Randomized, Placebo-controlled Study.

Safety and efficacy of psilocybin-assisted therapy for alcohol use disorder: Open-label extension of a phase II randomized controlled trial.

Therapists’ Perspectives on the Psychotherapeutic Support in Psilocybin Treatment for Major Depressive Disorder: Insights from a Randomized Controlled Trial

Effect of a Low-Dose Ketamine-Dexmedetomidine-Based Opioid-Sparing Anesthesia Protocol on Postoperative Quality of Recovery After Percutaneous Nephrolithotomy

Effects of Repeated Ketamine Infusions on Suicidal Ideation in Treatment-Resistant Depression and Associated Changes in Selected Plasma Biomarkers.

Effects of Psilocybin on Craving in Nicotine Dependence

Multi-center, randomized controlled efficacy and comparative-effectiveness study evaluating ketamine, stellate ganglion blocks, combination treatment, and sham treatments for posttraumatic stress disorder and traumatic brain injury-associated headache: a study protocol.

Evaluation of the Efficacy and Safety of Multimodal Sedation with Dexmedetomidine and Ketamine (Ketodex) at Different Ratios: A Randomized Clinical Trial

Reduced egocentricity after psilocybin in patients with alcohol use disorder: a pilot randomized controlled trial

No Heavy Drinking Days and Percentage of Days Abstinent in a Randomized Trial of Adjunctive Ketamine for Alcohol Use Disorder: Secondary Analysis of the KARE Trial

Symptom-level and network analyses of ketamine treatment in treatment-resistant depression: A pooled analysis of two randomized controlled trials.

Comparison of ketamine versus lignocaine intravenous infusion in refractory cancer pain: a prospective randomised double-blind controlled study.

A Study Comparing Oral Ketamine With Oral Midazolam for the Treatment of Major Depressive Episodes

The effect of the Apollo Neuro device on anxiety among participants who underwent ketamine assisted therapy: A non-randomized, observational cohort study

Behavioural Activation Therapy and Ketamine for Treatment-Resistant Depression

643. A mechanism-informed clinical trial of psilocybin-assisted therapy for opioid use disorder: rationale and neurobiological framework

717. Clinical trials, ethical dimensions, and the pathway of MDMA-assisted therapy in PTSD

THIS STUDY AIMS TO COMPARE TWO DRUGS KETAMINE AND TRAMAL IN PREVENTION OF SHIVERING IN PATIENTS UNDERGOING SPINAL ANESTHESIA STUDY POPULATION IS PT UNDERGOING C SECTION . DOSE OF KETAMINE IS 0.25mg/kg and That of TRAMAL 0.5mg/kg.

Intravenous Infusion of Low Dose Ketamine Versus Dexmedetomedine for Delirium Treatment in Acute Heart Failure

MDMA-AT for PTSD in Young Adults With Childhood Trauma

Testing Two Doses of Nebulized Ketamine for Postoperative Sore Throat

Nebulized Lidocaine And Ketamine Before Fiberoptic Bronchoscopy

Psilocybin-Assisted Group Integration Psychotherapy for Treatment-Resistant Depression

Trauma-informed Psilocybin Assisted Psychotherapy (TiPAP) for PTSD

Nebulized Ketamine for Severe Asthma Attacks in Children

Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin

Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life

Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study

Working Mechanisms and Effectiveness of IV Ketamine-assisted Psychotherapy on Depression in TRD Clients

Neural Effects of Intravenous N,N-dimethyltryptamine (DMT)

Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis

Intraperitoneal Ketamine Versus Fentanyl as Adjuvants to Bupivacaine in Laparoscopic Cholecystectomy

Efficacy in Relapse Prevention: Psilocybin in Alcohol Use Disorder With Depressive Symptoms

Psilocybin Efficacy With or Without Pimavanserin Pretreatment

Ketamine Added to Quadratus Lumborum Block for Pain Relief After Infant Pyeloplasty

KetAmine and Recovery After Mechanical VentilAtion ( KARMA )

MDMA Therapy in Veterans With PTSD

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

Group Retreat Psilocybin Therapy for Healthcare Clinicians With Loss of Meaning in Their Work and Symptoms of Depression

Oropharyngeoesophageal Topical Anesthesia Versus Intravenous Propofol -Ketamine Sedation for Upper Gastrointestinal Endoscopy

Ketamine Gargle for Pain After Pediatric Tonsillectomy

Comparison of Two Drugs ,i.e., Nalbuphine Vs Ketamine at Low Doses for the Peri-Operative Shivering Control in Patients Undergoing Gynaecological Surgery Under Spinal Anaesthesia

MDMA Assisted Therapy for BN

Comparison of Combined Dexmedetomidine and Ketamine (Ketodex) Versus Dexmedetomidine Alone in Awake Mapping for Deep Brain Stimulation: A Randomized Controlled Trial

Group Psilocybin-Assisted Therapy for Post-Traumatic Stress Disorder

Intraoperative Ketamine for Chronic Postoperative Pain After Open-Heart Surgery

Study of Psilocybin Under Anesthesia Controlled by EEG

Clinical trials
194 records available.