Daily source monitor · Global

Sources checked every day.
New records when found.

Papers, trials, safety signals, systematic reviews, case reports, preprints, and policy records—organized by source, date, evidence type, and editorial state.

Educational boundary. The bot detects source metadata; it does not decide what is medically true. “Submitted” means not yet interpreted or approved by Pō a Ao. A trial registration, preprint, abstract, or case report is not a treatment recommendation.

01 · 114 detected

Clinical trials

New and updated registry records. Registration does not establish safety, effectiveness, completion, or published results.

02 · 2 detected

Safety & interactions

Adverse-event, toxicity, contraindication, interaction, monitoring, and harm-reduction records.

03 · 8 detected

Systematic reviews

Systematic, scoping, umbrella, and meta-analytic records with methods and limitations still requiring appraisal.

04 · 4 detected

Case reports

Individual reports and small series that may identify signals but cannot estimate typical outcomes.

05 · 4 detected

Preprints

Public manuscripts that may not have completed peer review and may change or be withdrawn.

06 · 1 detected

Policy & law

Government and regulatory records. Legal meaning depends on exact activity, jurisdiction, entity, and date.

Automated discovery ledger

Most recently detected

Open all records

research-article
submitted

5-HT2A receptor activation is dispensable for psilocybin-induced fear extinction and neuroplasticity in mice.

Europe PMC · 9/15/2026 · psilocybin

Sources checked every day.New records when found.

Clinical trials

Safety & interactions

Systematic reviews

Case reports

Preprints

Policy & law

Most recently detected

5-HT2A receptor activation is dispensable for psilocybin-induced fear extinction and neuroplasticity in mice.

Implications of Potential US FDA Approval of Psychedelics or Psychedelic-Adjacents Such as Ibogaine for Pharmacy in Japan

Characterizing Psychedelic-Evoked Familiarity: A Comparative Study with Autobiographical and Déjà Vu Experiences.

Therapeutic Alliance and Perceived Closeness in MDMA-Assisted Therapy for Social Anxiety Disorder

MDMA administration reduces ethanol drinking and is associated with altered nociceptin and dynorphin system gene expression in alcohol-preferring rats.

Psilocybin restores spatial memory but not fronto-hippocampal synchrony in a rat model of Alzheimer's disease.

What Is Psilocybin?

Psilocybin.

Psychedelic 4-AcO-DMT attenuated looming-induced freezing behaviors by activating PrL &lt;sup&gt;CaMKIIα&lt;/sup&gt; neurons in mice.

MDMA-Assisted Therapy May Decrease PTSD Symptoms, Dissociation, Depression, and Functional Disability: A Systematic Review and Meta-Analysis.

A Two-Threshold Model of Psilocybin Response Explains Variability in Psychedelic-Assisted Therapy for Treatment-Resistant Depression

Psilocybin selectively suppresses novelty-induced grooming via 5-HT2B receptors: A microstructure analysis in Wistar rats.

Craving Reduction and Smoking Outcomes in Psilocybin-Assisted and Standard Cessation Care.

Exploratory Insights into 5-MeO-DMT Experiences on Reddit: A Thematic Analysis.

Who Is Reached by Supervised Psilocybin Services? Oregon Services Versus National Psilocybin Use

Higher signal diversity, network dysregulation, and increased well-being under DMT administration: An EEG study.

Psilocybin as an emerging anxiolytic: mechanisms, evidence, and open questions.

No more harm: A guiding principle of psychedelic drug policy

Psychedelic Renaissance: A New Paradigm in Mental Health

A Molecule-Resolved Bibliometric Analysis of PubMed-Indexed Psychedelic Research (2015–2025): Volume, Temporal Trends, and Publication Types

Boundaries or boundlessness? Toward knowledge co-creation in psychedelic-assisted therapy

The therapeutic potential of psychedelic drugs: past, present, and future

MDMA-Assisted Psychotherapy for Cluster B Personality Disorders: A Narrative Review of This Translational Framework for Relational Healing

Exploring Attitudes Toward MDMA-Assisted Therapy in Mental Health Care

One dose of Psilocybin modulates Brain Activity among Depressive patients : Preliminary Neuroimaging Results from the PSILODAC Study

Psilocybin-induced changes in electroencephalography link acute and long-term effects.

Daily briefing: Psilocybin blocks side-effect of chemotherapy in mice.

Long-term maintenance therapy with ketamine infusions for treatment-resistant depression: a retrospective chart review

Electroconvulsive Therapy vs. Ketamine: A Scoping Review and Meta-Analysis of Rapid-Acting Interventions for Acute Suicidality in Adults

Electroconvulsive Therapy and (Es)Ketamine in Treatment-Resistant Depression: A Review of Current Evidence

Sources checked every day.
New records when found.

Psychedelic 4-AcO-DMT attenuated looming-induced freezing behaviors by activating PrL <sup>CaMKIIα</sup> neurons in mice.